FALCARINOL BENEFITS

FALCARINOL BENEFITS cancer fighter
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FALCARINOL - A CANCER FIGHTER

Carrot has been known as an excellent source of vitamin A. Carrot
contains two important phytochemicals and they are carotenoids and
flavonoids. These phytochemicals are believed to help protect against
various chronic diseases such as cardiovascular disease and cancer,
and they may also promote night vision.

Recently, researchers have isolated a compound in carrots that may
have anticancer benefits. This compound is called falcarinol; studies
have shown that falcarinol might have benefits on colon cancer and
leukemia.

Researchers divided 24 male rats with precancerous colorectal
cancers into three groups and fed them three different diets: standard
rat food plus 10% freeze-dried carrots, standard food plus falcarinol
(in an amount equal to that found in carrots), or standard rat food
alone. After 18 weeks, the study showed that rats fed with carrots or
the falcarinol-fortified food were one-third less likely to develop
full-scale colorectal cancer than those fed with standard food. [1]
Researchers also found falcarinol to be an active compound with a
pronounced toxicity against acute lymphoblastic leukemia cell line
CEM-C7H2, with an IC(50) of 3.5 micromol/L. [2]

REFERENCES
[1] Kobaek-Larsen M et al, Inhibitory effects of feeding with carrots or
(-)-falcarinol on development of azoxymethane-induced preneoplastic
lesions in the rat colon. J Agric Food Chem. 2005 Mar 9;53(5):1823-7.
[2] Zidorn C et al, Polyacetylenes from the Apiaceae vegetables
carrot, celery, fennel, parsley, and parsnip and their cytotoxic
activities. J Agric Food Chem. 2005 Apr 6;53(7):2518-23.

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