What is Aloxi used for?
Aloxi is used to prevent nausea and vomiting that happens:
right away with certain anti-cancer medicines (chemotherapy).
later after taking certain anti-cancer medicines
Aloxi is not used to treat the nausea and vomiting you may already have. Aloxi has not
been studied in children under 18 years of age.
Who should not take Aloxi?
Do not take Aloxi if you are allergic to Aloxi or any of its ingredients.
General Precautions with Aloxi:
If you are allergic to other medicines like Aloxi, such as ondansetron (Zofran),
dolasetron (Anzemet), or granisetron (Kytril), you are more likely to have an allergic
reaction with Aloxi.
Aloxi may affect your heartbeat. This may cause serious problems, especially in
already have heartbeat problems or irregular heartbeat (especially a condition called
are taking medicine to control a heartbeat problem
are taking medicines called diuretics ("water pills")
have low levels of potassium and magnesium in their blood
What should I tell my health care provider?
Tell your health care provider:
if you are pregnant or planning to become pregnant.
if you are breast-feeding.
Tell your health care provider about ALL the medicines you take, including prescription
and non-prescription medicines, vitamins, and herbal supplements. Some medicines
may affect how Aloxi works or Aloxi may affect how your other medicines work.
What are some possible side effects of Aloxi? (This is NOT a complete list of side
effects reported with Aloxi. Your health care provider or pharmacist can discuss with
you a more complete list of side effects.)
Some common side effects with Aloxi include:
stomach area pain
HELSINN is a privately owned pharmaceutical group with headquarters in Switzerland.
Helsinn's core business is the licensing of pharmaceuticals in therapeutic areas
(oncology, cancer supportive care, pain and inflammation, gastrointestinal). Helsinn's
key products in the US are Aloxi® (palonosetron), distributed by Eisai Inc., USA, and
For more detailed information about Aloxi, ask your health care provider or
pharmacist. ALL RIGHTS RESERVED 2008
 Squashing a Queasy Stomach curetoday.com 2008  Zealand Pharma and
Helsinn Healthcare Sign a Partnering Agreement for ZP1846, a novel GLP-2 agonist
Chemotherapy agents stimulate nausea and vomiting. Certain drugs, such as cisplatin and
Adriamycin (doxorubicin), are more closely associated with this side effect. Severe vomiting leads to
dehydration. With chemotherapy agents likely to cause acute nausea and vomiting, the American
Society of Clinical Oncology recommends a three-drug combination: 5-HT3 antagonist—Anzemet
(dolasetron), Kytril/Sancuso (granisetron), Zofran (ondansetron), or Aloxi (palonosetron).