Researchers from Kao Corporation, Tokyo, Japan:

Chlorogenic acids (CGA) in green coffee bean extract (GCE) reduce
blood pressure in spontaneously hypertensive rats and humans. The
researchers examined the blood pressure-lowering effect and safety of
CGA in patients with mild hypertension through a placebo-controlled,
randomized clinical trial. Subjects (n = 28) were randomized to receive
treatment with CGA (140 mg/day) from GCE or placebo. They found that
blood pressure (systolic and diastolic) decreased significantly during the
ingestion period in the CGA group but not the placebo group. They
concluded that CGA from GCE is effective in decreasing blood pressure
and safe for patients with mild hypertension. [1]

[1] The blood pressure-lowering effect and safety of chlorogenic acid
from green coffee bean extract in essential hypertension.
green coffee bean extract
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