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What is Celadrin?

Celadrin is a registered trademark of Imagenetrix Corporation.
Celadrin is also a proprietary blend of esterified fatty acid
carbons of Myristate, Myristoeleate, Laurate, Oleate, Palmitate,
and Palmitoleate in a base of tapioca and silica). According to
the manufacturer, Celadrin is made from a patented complex
blend of special esterified fatty acids, derived from bovine tallow
oil. Some marketers promote Celadrin as a supplement help
support healthy joint function and mobility, without the side effects
often associated with other therapies. Serving size for most
Celadrin products in market is 1500 mg.

Are there research study about Celadrin? There are only 2-3
studies reported (up to the date that I prepare this summary

In a study, Hesslink et al evaluated 64 patients with chronic knee
osteoarthritis at baseline, at 30 and 68 days after consuming
either placebo or cetylated fatty acids (Celadrin; n = 33). The
evaluation included physician assessment, knee range of motion
with goniometry, and the Lequesne Algofunctional Index. They
found that patients treated with Celadrin had some improvement
in knee flexion and neither group reported improvement in knee
extension. [1]

In another study, a researcher group showed that 1 month of
treatment with a topical Celadrin cream consisting of cetylated
fatty acids (with or without methol) was effective to reduce pain
and improve functional performance in individuals with
osteoarthritis to a certain extent. [2]

Compared to baseline, treatment of Celadrin or Celadrin cream
shows improvements in symptoms of osteoarthritis. [1,2]
However, there is no published report indicating that Celadrin is
superior to other common healthy joint supplements, such as
Glucosamine, Chondroitin, MSM and SAMe.

Some manufacturers even combine Celadrin with MSM to have
"additive benefits". MSM is the biologically active source of sulfur
is essential in the formation of both collagen (a key component in
cartilage) and sulfur amino acids such as methionine and
cysteine. While, other include glucosamine in the product, such
as Celadrin � empowers glucosamine, to perform faster and
more efficiently in building joint cartilage as well as accelerating
and promoting joint health [3]. Glucosamine helps in the
rebuilding of cartilage & the overall structure of the joint and has
shown positive effects on people with osteoarthritis. While, some
other manufacturers just simply combine glucosamine,
chondroitin and MSM together in their products.

Is there any side-effect of Celadrin? Is Celadrin safe? The studies
on Celadrin side effects are limited.  Probably, Celadrin is safe
for short-term use. However, more studies are needed to ensure
its safety for long-term use.

Which supplement should I use for joint health? Users should
consider those have been in the market for a longer time, and
with a good reputation.

Reference:[1] Hesslink R Jr et al, Cetylated fatty acids improve knee function in patients with
osteoarthritis. J Rheumatol. 2002 Aug;29(8):1708-12. [2] Kraemer WJ et al, A cetylated fatty
acid topical cream with menthol reduces pain and improves functional performance in
individuals with arthritis. J Strength Cond Res. 2005 May;19(2):475-80. [3] www. celadrin.com

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before using this product. Using this product is at your own risk. All right reserved 2008. Do not
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Discuss with your doctor before taking any alternative medicine. This article is for
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