Ginseng ginkgo biloba extract benefits
Ginseng ginkgo ADHD
GINSENG GINKGO BILOBA HEALTH BENEFITS- RESEARCH FINDINGS

Neurological, Cognitive Conditions

In vitro Studies
Amyloid beta (Aβ or Abeta) is a peptide of 36–43 amino acids that is processed from the amyloid precursor protein. While
best known as a component of amyloid plaques. Amyloid beta-peptide has been found to have a role in the free-radical
oxidative-stress model of neurotoxicity in
Alzheimer's disease. Hydrogen peroxide level was elevated with AD-associated
transgenic cells expressing the amyloid beta-peptide. Treatment of these cells with Ginkgo biloba extract significantly
attenuated the basal as well as the hydrogen peroxide-realted reactive oxygen species levels. [1] In a study, extracts of
ginseng and ginkgo biloba showed a protective effects on rat primary cultured neurons damaged by Abeta(1-40). [A4] Thus,
these basic studies suggest extracts of Ginkgo biloba and ginseng may benefit people with certain neurological conditions.

Animal Study
Petkov et al studied the effects of the ginseng ginkgo biloba extracts on young and old rats using some conditioned-reflex
methods. The extracts were administered orally for 7 days before the study. They found that the two extracts and their
combination improved the retention of learned behavior. Ginseng ginkgo biloba combination is particularly promising in
geriatric practice. [3] The results of this animal study are in line with the findings in the test-tube studies - extracts of ginkgo
biloba and ginseng may benefit people at risk of certain neurological conditions.

Clinical Trials
To further understand how extracts of ginkgo biloba and ginseng may benefit people at risk of certain neurological conditions.
Dr. Wesnes and colleagues evaluated the effect of a
ginseng ginkgo combination on cognitive function of 64 healthy
subjects (aged 40-65) in a 90-day, double blind, placebo-controlled, parallel-group study. On Day 90 at 1 hour post morning
dosing, dose-related improvements were seen on the Cognitive Drug Research tests, the 320 mg dose being significantly
superior to placebo.They assessed the subjects' performance on cycle ergometry and various questionnaires before and
after dosing. They found that a 80-mg dose produced a significant benefit on the ergometry assessment of heart rate at
maximum load. [2]

A commercial herbal preparation of ginkgo biloba and Panax ginseng (Memo®) was used in a study of mild cognitive
impairment. Sixty-six subjects  with forgetfulness and mild cognitive impairment were randomly divided into an experimental
group treated with royal jelly, ginkgo biloba and Panax ginseng combo preparation before breakfast daily for 4 weeks and a
control group who took placebo. The researchers in the study found the mean change in the mild "cognitive impairment
score" in the group treated with Memo for 4 weeks was significantly greater than in the control group. The authors suggest
the combination of royal jelly, ginkgo biloba and Panax ginseng may benefit people at risk of Alzheimer's disease and
dementia. [A1] Please, note that royal jelly is present in this extract-preparation.

Blood Pressure

A preparation containing 60 mg ginkgo biloba and 100 mg ginseng was administrated to 10 voluntary subjects with a
mean age of 26. The researchers found their systolic blood pressure decreased significantly at a double dose and single
dose. While, diastolic blood pressure decreased only at the double dose.Hemorrheological and circulatory effects of gincosan
(a combination of ginseng and ginkgo biloba). [4] Thus, intake of a ginkgo biloba and ginseng combo may benefit people at
risk of hypertension, but users should discuss with their medical doctors before taking a preparation containing ginkgo biloba
and/or ginseng.

ADHD
Does ginseng ginkgo benefits people suffered from ADHD? A combination herbal product containing American ginseng
extract, Panax quinquefolium, (200 mg) and Ginkgo biloba extract (50 mg) (AD-FX; CV Technologies, Edmonton, Alta.) was
tested for its benefits on the symptoms of attention-deficit hyperactivity disorder (ADHD) in 36 children suffered from ADHD.
After 4 weeks of treatment, the 44% of subjects exhibiting improvement for the social problems attribute and 74% for the
Conners' ADHD index and the DSM-IV hyperactive-impulsive attribute. Five (14%) of 36 subjects reported adverse side
effects. More studies are needed to clarify ginseng ginkgo ADHD. [5]
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GINSENG GINKGO BILOBA SIDE EFFECTS
Researchers have reviewed 56 articles and found that both ginkgo and ginseng may cause hypertension. [A2] There is also a
report that ginkgo biloba and ginseng interact with drugs. [A3]


As mentioned in the first section, ginseng and ginkgo biloba have similar biological effects or potential benefits towards our
body. Consequently, their combination potentiates their beneficial effects, however, their combination theoretically may also
potentiate their side effects. Do not take doses more the recommended dosage. Users should consult with their doctors on
the potential benefits and side effects of any supplements, before taking them. The information is not intended to be a
substitute for professional medical advice. It is important for readers to seek the advice of a physician about any medical
condition or symptom or the benefits and side effects of a supplement contatining ginseng and ginkgo biloba. Finally, please,
do not transfer the article to other website. Thanks.


Related Articles: Ginseng benefits, Ginseng Side Effects, Siberian Ginseng Ginkgo Biloba            
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Reference
Ginseng ginkgo biloba benefits: [1] Elevation of oxidative free radicals in Alzheimer's disease models can be attenuated by Ginkgo biloba extract
EGb 761. Smith et al,  J Alzheimers Dis. 203 Aug;5(4):287-300]. [2] Wesnes et al,
The cognitive, subjective, and physical effects of a
ginseng ginkgo combination in health volunteers with neurasthenic complaints. Psychopharmacol Bull. 1997;33(4):677-83. [3]
Petkov et al. Memory effects of standardized extracts of Panax ginseng (G115), Ginkgo biloba (GK 501) and their combination
Gincosan (PHL-00701).Bulgarian Academy of Sciences, Sofia. Planta Med. 1993 Apr;59(2):106-14. [4] Kiesewetter et al.  Int J
Clin Pharmacol Ther Toxicol. 1992 Mar;30(3):97-102.
Ginseng ginkgo ADHD: [5] Lyon MR, et al, Effect of the herbal extract combination
Panax quinquefolium and Ginkgo biloba on attention-deficit hyperactivity disorder: a pilot study. J Psychiatry Neurosci. 2001 May;26(3):221-8. [A1]
Yakoot M, et al, Effect of Memo®, a natural formula combination, on Mini-Mental State Examination scores in patients with mild cognitive
impairment. Clin Interv Aging. 2013;8:975-81. [A2] Jalili J et al, Herbal products that may contribute to hypertension. Plast Reconstr Surg. 2013 Jan;
131(1):168-73. [A3] Chen XW et al, Herb-drug interactions and mechanistic and clinical considerations. Curr Drug Metab. 2012 Jun 1;13(5):640-
51. [A4] Cong W, et al, [Protective effects of ginseng-ginko extracts combination on rat primary cultured neurons induced by Abeta(1-40)]. et al,
Zhongguo Zhong Yao Za Zhi. 2011 Apr;36(7):908-11.
Ginseng Ginkgo Biloba Extracts
Ginkgo Biloba  is best known for its ability to enhance circulation systemically. Its action is directly related to the vaso-relaxing
activity. Thus, Ginkgo Biloba can lower blood pressure and inhibit platelet aggregation. Scientific studies have shown its
promise on cognition-enhancement (booster). If used during the early stages of Alzheimer's disease, the mental deterioration
may slow down. The user can expect results only after taking the product for 3-6 months on a daily basis. Contra indications
include not taking the product before surgery, so you should check with your doctor before undergoing any procedure.        

Ginkgo biloba has been combined with ginseng for a few conditions, and the researchers were excited for the potential
benefits of this combination. Why ginkgo biloba is combined with ginseng? It is because
ginseng and ginkgo biloba have a
number of similarities. Firstly, both ginseng and ginkgo biloba has been used in traditional medicine for thousands of years.
Ginseng and ginkgo biloba are both believed to have benefits on memory, actually, there are a few scientific evidence for
their health benefits. Further, ginseng and gingko biloba are both may benefit or support many conditions. Ginseng and
ginkgo biloba both have been studied extensively about their potential health benefits. Ginseng and ginkgo biloba both may
benefits our central nervous system,  circulatory system and reproductive system. Combining both ginseng and ginkgo biloba
proved to be effective in memory loss particularly those that are brought about by Alzheimer’s disease, and we shall discuss
the research findings on this aspect in the next section.
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