The Health Benefits of Tangerine Peel  chen pi  陳皮

Pericarpium Citri Reticulatae, Citrus reticulata Blanco, chinpi, hong ju, da hong pao, chuan
ju, 红橘、大红袍、川橘

What is its traditionally use?

Traditionally, it has been used to raise the blood pressure, stimulate blood vessels, decrease the
movement of digestive tract and uterus. It contains nobiletin, pinenes etc. [1] Its peel contains
hesperidin, neohesperidin, nobiletin and tangeritin. [4]

Are there any health benefits of Tangerine Peel (with scientific support)?

Researchers from Korea found it has cholesterol-lowering effects in a rat study. Bok SH
and co-workers from Korea Institute of Bioscience and Biotechnology, Korea [2] wrote:
The inhibition of HMG-CoA reductase and ACAT activities resulting from the supplementation of
either tangerine-peel extract or a combination of its bioflavonoids could account for the decrease in
fecal neutral sterol that appears to compensate for the decreased cholesterol biosynthesis in the

Researchers showed its anti-cancer activities in cell studies.

Murakami A and co-workers from Kinki University, Japan, wrote [3]:
Citrus fruit intake is
known to be associated with a reduction of cancer incidence. The inhibitory activities of peel parts
were largely found to be higher than those of the corresponding juice sac parts. In particular, the peel
portion of Dancy tangerine (Citrus tangerinia) showed marked anti-oxidative activities in these

Korean researchers found that Citrus reticulata Blanco (CR) extract, the immature tangerine peel,
possessed of activities against human gastric cancer cell line SNU-668. [5]

Researchers believe peels can benefit people suffered from cardiovascular and neural diseases
such as Parkinson's disease. [6, 7]

[1] [2] Bok SH, Lee SH, Park YB, Bae KH, Son KH, Jeong TS, Choi MS.
Plasma and hepatic cholesterol and hepatic activities of 3-hydroxy-3-methyl-glutaryl-CoA reductase
and acyl CoA: cholesterol transferase are lower in rats fed citrus peel extract or a mixture of citrus
bioflavonoids. J Nutr. 1999 Jun;129(6):1182-5. [3] Murakami A, Nakamura Y, Ohto Y, Yano M,
Koshiba T, Koshimizu K, Tokuda H, Nishino H, Ohigashi H. Suppressive effects of citrus fruits on
free radical generation and nobiletin, an anti-inflammatory polymethoxyflavonoid. Biofactors. 2000;
12(1-4):187-92. [4] Guo XL, Wang TJ, Guo MJ, Chen Y. Studies on chemical constituents of
processed green tangerine peel, Zhongguo Zhong Yao Za Zhi. 2000 Mar;25(3):146-8. [5] Kim MJ,
Park HJ, Hong MS, Park HJ, Kim MS, Leem KH, Kim JB, Kim YJ, Kim HK., Citrus Reticulata blanco
induces apoptosis in human gastric cancer cells SNU-668., Nutr Cancer. 2005;51(1):78-82. [6]  
Rincón AM, Vásquez AM, Padilla FC. Chemical composition and bioactive compounds of flour of
orange (Citrus sinensis), tangerine (Citrus reticulata) and grapefruit (Citrus paradisi) peels
cultivated in Venezuela Arch Latinoam Nutr. 2005 Sep;55(3):305-10. [7] Datla KP, Zbarsky V, Rai
D, Parkar S, Osakabe N, Aruoma OI, Dexter DT. Short-term supplementation with plant extracts rich
in flavonoids protect nigrostriatal dopaminergic neurons in a rat model of Parkinson's disease. J Am
Coll Nutr. 2007 Aug;26(4):341-9.