Definitions

Atheroma - Fatty material that can build up within the walls of the arteries and a reduction of blood flow, on
to which clots may form.

Atheromatosis - The presence or the development of many atheromas.

Atheromatous - Pertaining to atheroma

Atheromatous plaque - A well-demarcated swelling on the intimal surface of an artery; produced by intimal
lipid deposit.

Atheroma Formation
Atheroma is a bulging yellow mass or "plaque" that forms within the walls ling the arteries. It contain a
mixture of fat, cholesterol, inflammatory cells and fibrous scar tissue. When it deposit onto the inner well of
an artery, it reduces its inner diameter.

Deposition of atherma to arterial walls will lead to hardening of the arteries-
atherosclerosis. Thus, it
narrows the pathway for blood at coronary arteries. Atherosclerosis can restrict as much as 70% of the
blood that flows through the coronary arteries-myocardial ischemia. Consequently, this lack of blood will
trigger an episode of angina.

ANGINA
Angina is a pain or discomfort in the chest caused by insufficient blood flow to the heart muscle. About 3-5%
of American suffer from angina. The most common cause is coronary artery disease (CAD). The common
factors for CAD include male gender, cigarette smoking, high cholesterol, high blood pressure, diabetes and
obesity.

Beside medical treatment, the prevention include stopping smoking, weight lose (if you are overweight) and
control of blood pressure, diabetes, and cholesterol.

CHOLESTEROL

More than 50 million Americans have elevated cholesterol levels, this elevated cholesterol level is a major
risk factor for coronary heart disease.

Cholesterol is transported through the bloodstream by a vehicle called lipoprotein. There are three types of
lipoprotein: high-density lipoprotein (HDL), low-density lipoprotein (LDL), and very low-density lipoprotein
(VLDL). LDL carries fats from the liver to the other parts of the body, while HDL carries fat back to the liver.
The higher the LDL level, the more fat we have in circulation and the greater risk we have for fat-related
diseases-atherosclerosis. In contrast, HDL carries fat back to the liver, i.e. HDL removes fat from the
circulation. We always want more HDL but less LDL, or a high HDL/LDL ratio. Consequently, people always
call HDL as good cholesterol, LDL as bad cholesterol.

                                                
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atheroma, atheromatosis, atheromatous disease
atheromas definition              August 30, 2011