Atheroma
Formation
Atheroma is a bulging yellow mass or "plaque" that forms within the walls
ling the arteries. It contain a mixture of fat, cholesterol, inflammatory cells
and fibrous scar tissue. When it deposit onto the inner well of an artery, it
reduces its inner diameter.
Deposition of atherma to arterial walls will lead to hardening of the
arteries-atherosclerosis. Thus, it narrows the pathway for blood at coronary
arteries. Atherosclerosis can restrict as much as 70% of the blood that
flows through the coronary arteries-myocardial ischemia. Consequently,
this lack of blood will trigger an episode of angina.
ANGINA
Angina is a pain or discomfort in the chest caused by insufficient blood flow
to the heart muscle. About 3-5% of American suffer from angina. The most
common cause is coronary artery disease (CAD). The common factors for
CAD include male gender, cigarette smoking, high cholesterol, high blood
pressure, diabetes and obesity.
Beside medical treatment, the prevention include stopping smoking,
weight lose (if you are overweight) and control of blood pressure, diabetes,
and cholesterol.
CHOLESTEROL
More than 50 million Americans have elevated cholesterol levels, this
elevated cholesterol level is a major risk factor for coronary heart disease.
Cholesterol is transported through the bloodstream by a vehicle called
lipoprotein. There are three types of lipoprotein: high-density lipoprotein
(HDL), low-density lipoprotein (LDL), and very low-density lipoprotein
(VLDL). LDL carries fats from the liver to the other parts of the body, while
HDL carries fat back to the liver. The higher the LDL level, the more fat we
have in circulation and the greater risk we have for fat-related
diseases-atherosclerosis. In contrast, HDL carries fat back to the liver, i.e.
HDL removes fat from the circulation. We always want more HDL but less
LDL, or a high HDL/LDL ratio. Consequently, people always call HDL as
good cholesterol, LDL as bad cholesterol.
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