chamomile benefits, chamomile benefits, chamomile side effects,
chamomile, tea, extract, herb, weight loss? December 31, 2011  zhion@zhion.com   
Chamomile tea side effects
Chamomile is generally considered safe and nontoxic. Side effects are extremely rare for health users. However, if you
are on medical treatment or if you are taking high doses of chamomile herb, you should consult with your doctor before
use this extract or related products. A study has shown that chamomile preparations contain constituents inhibiting the
activities of major human drug metabolizing enzymes, especially the drugs with elimination route of cytochromes
(especially CYP1A2). [1] Another study using rat as a model has shown that high doses of chamomile essential oil may
cause a depressive effect [i.e. toxicity]. [4]

If you suffer from allergies to plants of the Compositae family (a large group including such flowers as daisies,
ragweed, asters and chrysanthemums), you have to be cautious about using chamomile herb, tea or supplements. The
allergic reactions may include skin rashes and bronchial constriction. However, most people can use this herb with no
problem.
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REFERENCE [1] Ganzera M et al, Inhibitory effects of the essential oil of chamomile (Matricaria recutita L.) and its
major constituents on human cytochrome P450 enzymes. Life Sci. 2005 Aug 30 2005. [2] Weseler A et al, A novel
colorimetric broth microdilution method to determine the minimum inhibitory concentration (MIC) of antibiotics and
essential oils against Helicobacter pylori. Pharmazie. 2005 Jul;60(7):498-502. [3] Shinomiya K et al, Hypnotic activities
of chamomile and passiflora extracts in sleep-disturbed rats. Biol Pharm Bull. 2005 May;28(5):808-10. [4] Fundaro A et
al, Action of essential oils of chamomile, cinnamon, absinthium, mace and origanum on operant conditioning behavior
of the rat Boll Soc Ital Biol Sper. 1980 Nov 30;56(22):2375-80. [5] Mazokopakis EE et al,  Wild chamomile (Matricaria
recutita L.) mouthwashes in methotrexate-induced oral mucositis. Phytomedicine. 2005 Jan;12(1-2):25-7. [8] Glowania
HJ et al Effect of chamomile on wound healing--a clinical double-blind study Z Hautkr. 1987 Sep 1;62(17):1262, 1267-
71. [A1] Amsterdam JD, Yimei L, Soeller I, et al. A randomized, double-blind, placebo-controlled trial of oral Matricaria
recutita (chamomile) extract therapy for generalized anxiety disorder. Journal of Clinical Psychopharmacology. 2009
Aug;29(4):378–382. [2]
http://naturaldatabase.therapeuticresearch.com/ce/ceCourse.aspx?s=ND&cs=&pc=09-
28&cec=1&pm=5  [A3]Rügge SD Evidence of dermatological effects of chamomile Ugeskr Laeger. 2010 Dec 13;172
(50):3492-6. [A4] Al-Hashem FH. Gastroprotective effects of aqueous extract of Chamomilla recutita against ethanol-
induced gastric ulcers. Saudi Med J. 2010 Nov;31(11):1211-6.
Discuss with your doctor before taking any alternative medicine. This article is for
reference only, it is not a medical advice. All rights reserved. Do not copy this article to
other website or blog.
Chamomile Extract, Tea, Reviews
Chamomile is a soothing, gentle relaxant that may benefit a variety of complaints from stress to menstrual cramps, as some websites claim. The
word chamomile is derived from the Greek chamos melos, meaning ground apple, referring to the plant's low growing habit and the fact that the
chamomile herb has a satisfying, apple-like aroma and flavor. It's most often taken as a mild “healthful beverage tea” -
chamomile tea. Chamomile
extracts are also added to healing creams and lotions or packaged as pills and tinctures.

There are two species of chamomile- German chamomile and Roman chamomile. German chamomile(Matricaria recutita) is common in North
America and central Europe, while the Roman chamomile (Chamaemelum nobile or Anthemis nobilis) is more commonly sold in England. German
chamomile plant is a sweet-scented, smooth, branched annual growing to 2 1/2 ft. in height, while, Roman chamomile plant is an aromatic, creeping
perennial, growing to one foot in height. Though German chamomile and Roman chamomile are different, they have been used interchangeably.
However, they may benefit people suffered from similar health conditions.

The flowerheads of Roman chamomile are used to make medicine. Roman chamomile may benefit people suffered from various digestive conditions
such as indigestion, nausea, vomiting, loss of appetite, and flatulence (due to mental stress). Some women use chamomile for morning sickness
and painful menstrual periods. It is also used for pain and swelling of the lining of the nose and mouth, sinusitis, and joint (rheumatic) disorders.
Chamomile is applied in tea, pill and capsules. [A2]

Charmomile may benefit people suffered from certain skin conditons. Roman chamomile is applied directly to the skin inflammation and as a germ-
killer in ointments, creams, and gels used to treat cracked nipples, sore gums, and irritation of the skin. It is also used topically for wounds, burns,
eczema, frostbite, diaper rash, bedsores, and hemorrhoids. [A2]
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Potential Health Benefits of Chamomile Extracts, Tea, Supplements - Capsules and Tablets

Anxiety Symptoms
Generalized anxiety disorder (GAD) has a wide array of psychological and physical symptoms. Although prescription
drugs can help, they often have undesirable side effects. One traditional remedy in widespread use is the herb
chamomile. NCCAM-funded researchers at the University of Pennsylvania recently conducted a randomized, double-
blind, placebo-controlled trial to test the effects of chamomile extract in patients diagnosed with mild to moderate GAD.
For 8 weeks, the 57 participants received either chamomile capsules containing 220 mg of pharmaceutical-grade
extract from Matricaria recutita (German chamomile), standardized to 1.2 percent of the constituent apigenin; or
chamomile-scented placebo capsules containing lactose. The initial dose of one capsule daily was increased to two
capsules daily at week 2; dosages were then adjusted incrementally (up to five capsules) in some participants.
Researchers used the Hamilton Anxiety Rating (HAM-A) and other tests to measure changes in anxiety symptoms over
the course of the study; dosage adjustments were based on HAM-A scores.

Compared with placebo, chamomile was associated with a greater reduction in mean HAM-A scores—the study's
primary outcome measure. The authors concluded that chamomile may have modest benefits for some people with
mild to moderate GAD. They also point out that other chamomile species, preparations (e.g., extracts standardized to
constituents other than apigenin), and formulations (e.g., oil or tea) might produce different results.

Cancer
Intake of Chamomile tea or extracts may benefit people at risk of certain cancers. A study shows that the combination
of 5-fluorouracil (a anti-cancer agent) and bisabololoxide (one of main constituents in German chamomile) further
inhibited the growth of human
leukemia K562 cells although the additive inhibition of growth by bisabololoxide A
became smaller as the concentration of 5-fluorouracil increased. [A5]

Gastric Issues
Chamomile tea or extracts may benefit people suffered from certain gastric conditions. In a study, 60 white albino rats
were divided into 5 groups. Group 1 (control group) was treated with deionized water for 28 days; animals in group 2 to
group 5 received zero, 0.5, 1, or 2 gm/kg ACE for 27 days. Stomach ulcerations were induced by orally administering a
single dose of 70% ethanol on day 28. Compared to placebo-treated rats, the ulcer index decreased significantly in a
chamomilla recutita extract dose-dependent manner in the treated rats. [A4]

Infections
Chamomile may have benefits for those suffered from certain infections. Helicobacter pylori infections have been
associated with the pathogenesis of a number of stomach and gastroduodenal diseases. A studies has shown that
chamomile oil inhibits the bacterial growth in extraordinarily low concentrations of 0.0075% (v/v) and about 65
microg/ml, respectively. The bactericidal concentrations were generally one to two dilution steps higher.  Therefore,
the herb may benefit those suffered from certain gastro-duodenal diseases. [2]

Inflammation
Chamomile extracts and chamomile tea are widely used herbal preparations for the treatment of minor illnesses (e.g.
indigestion, inflammation). [1] Researchers reported that wild chamomile mouthwashes relieved methotrexate-induced
oral mucositis in a patient with rheumatoid arthritis. Oral mucositis is a known complication of methotrexate (MTX)
therapy. [5] Thus, intake of chamomile extracts or tea may benefit people at risk of certain type of inflammation.

Sleep
A study of sleep-disturbed model rats has shown that chamomile extract has benzodiazepine-like hypnotic activity. A
significant decrease in sleep latency was observed with chamomile extract at a dose of 300 mg/kg. Flumazenil, a
benzodiazepine receptor antagonist, at a dose of 3 mg/kg showed a significant antagonistic effect on the shortening in
sleep latency induced by chamomile extract. [3]Thus, chamomile extracts may benefit people suffered from certain
sleep issues, however, more studies are needed to support the claims.

Skin Conditions and Wounds
Extracts and decoctions made from this plant are often recommended for treatment of a number of skin diseases e.g.
inflammation, wounds and itching. [A3] A double-blind trial of 14 patients has demonstrated the therapeutic efficacy of
chamomile extract on weeping wound area after dermabrasion of tattoos. [8] Thus, chamomile may benefit people with
certain skin issues.

Weight Loss
Chomomile is found in some weight loss preparations, but there is no scientific report that it helps weight loss. (up to
the date of August 20, 2011) Thus, its effect on weight loss is unknown.
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