| BLACK SOYBEAN HEALTH BENEFITS AND SIDE EFFECTS |
Yellow soybean (or soya bean) has been known its benefits of
cholesterol-lowering. Now, a recent animal study in Korea suggested that
intake of black soya beans could also benefit high cholesterol and may
help prevent diabetes. In this animal study, the group eating black soya
prevented weight gain and improved cholesterol levels. This finding can
be beneficial to diabetes. It is because the key problem in Type 2
diabetes is the impairment of insulin action, mainly as a result of excess
abdominal adipose tissue - so loss of weight is believed to benefit Type 2
diabetes. [14]
In fact, a while ago, Japanese researchers found black soybean had an
inhibitory effect of black soybeans on low density lipoprotein (LDL)
oxidation. The extract from black soybean also had a longer LDL
oxidation lag time than that from yellow soybean. [9]
Black soya bean (soybean) is rich in antioxidants.
Black soybean [Glycine max (L.) Merr.] has been used as a health food
and herb in China for hundreds of years. [1] Several studies have
demonstrated that the daily intakes of soy foods were associated with a
reduced cardiovascular risk. [9]
Researchers from Japan found black soybean seed coat contained a
variety of procyanidins, And, they showed high radical-scavenging
activities of these procyanidins in test-tube studies. [2] While researchers
from Korea considered that the seed coat of black soybean was a good
source of anthocyanin pigments such as cyanidin-3-glucoside and
delphinidin-3-glucoside. [3]
What are other potential benefits of eating black soya
bean (soybean)?
Eating black soya bean may reduce the risk of cancer and heart
diseases.
Korean researchers showed that anthocyanins isolated from black
soybean seed coat inhibited TNF-alpha-induced vascular cell adhesion
molecule-1, intracellular adhesion molecule-1, and cyclooxygenase-2
levels. Further, anthocyanins protected myocardiac injury from
ischemia-reperfusion in rats. Thus, anthocyanins from black soybean
seed coat benefit conditions like cardiovascular disorders. [11]
Researchers from Taiwan extracted a polysaccharide from the black
soybean. They found that this polysaccharide indirectly inhibited
proliferation and induced differentiation of human leukemic U937 cells via
activation of mononuclear cells in the study. [1]
Researchers found tryptophol from black soybean vinegar could inhibit
the proliferation of human monoblastic leukemia U937 cells by inducing
apoptosis via a pathway involving caspase-8 followed by caspase-3,
without affecting normal lymphocytes. [13]
Researchers from Taiwan noticed the promotion of myelopoiesis by an
active polysaccharide of black soybean in a study of murine spleen cells.
They also found that oral administration of that active polysaccharide of
black soybean in mice restored the leukocyte counts reduced by total
body-irradiation and 5-fluorouracil (5-FU) treatment. [6]
Eating black soya bean may enhance pregnancy.
Chinese researchers demonstrated the estrogenic activities of an
ethanol extract of black soybean. They found that the ethanol extract of
black soybean stimulated the growth of MCF-7 cells and increased the
expression of estrogen receptor-responsive gene in their study. [12] A
clinical study of 36 patients in Japan demonstrated that intake of black
soybean powder for six months improved ovulation and pregnancy. [10]
Black soya bean may have anti-fungi, anti-viral activities.
Hong Kong researchers isolated a monomeric protein, with a molecular
mass of 25 kDa and an N-terminal sequence resembling a segment of
chitin synthase from the seeds of the black soybean Glycine soja. This
protein, glysojanin, demonstrated potent antifungal activity against the
fungi Fusarium oxysporum and Mycosphaerella arachidicola. It also
inhibited HIV-1 reverse transcriptase in test-tubes. [5]
Japanese researchers found significant antiviral activities of a hot-water
black soybean extract in a test-tube study. This black soybean extract
showed significant antiviral activity against human adenovirus type 1 and
coxsackievirus B1 in a dose-dependent manner, [4]
ALL RIGHTS RESERVED ZHION 2007. THIS REFERENCE IS FOR YOUR REFERENCE ONLY.
CONSULT WITH YOUR DOCTOR FOR ANY QUESTIONS. [1] Liao HF et al, Isolation and
characterization of an active compound from black soybean [Glycine max (L.) Merr.] and its effect
on proliferation and differentiation of human leukemic U937 cells. Anticancer Drugs. 2001
Nov;12(10):841-6. [2] Takahata Y, et al, Highly polymerized procyanidins in brown soybean seed
coat with a high radical-scavenging activity. J Agric Food Chem. 2001 Dec;49(12):5843-7. [3]
Choung MG, et al, Isolation and determination of anthocyanins in seed coats of black soybean
(Glycine max (L.) Merr.). J Agric Food Chem. 2001 Dec;49(12):5848-51. [4] Yamai M, et al,
Antiviral activity of a hot water extract of black soybean against a human respiratory illness virus.
Biosci Biotechnol Biochem. 2003 May;67(5):1071-9. [5] Ngai PH, Ng TB. Purification of
glysojanin, an antifungal protein, from the black soybean Glycine soja. Biochem Cell Biol. 2003
Dec;81(6):387-94. [6] Liao HF, et al, A novel polysaccharide of black soybean promotes
myelopoiesis and reconstitutes bone marrow after 5-flurouracil- and irradiation-induced
myelosuppression. Life Sci. 2005 Jun 10;77(4):400-13. Epub 2005 Feb 25. [9] Takahashi R, et al,
Antioxidant activities of black and yellow soybeans against low density lipoprotein oxidation. J
Agric Food Chem. 2005 Jun 1;53(11):4578-82. [10] Kohama T, et al, The effect of soybeans on
the anovulatory cycle. J Med Food. 2005 Winter;8(4):550-1. [11] Kim HJ, et al, Anthocyanins from
soybean seed coat inhibit the expression of TNF-alpha-induced genes associated with
ischemia/reperfusion in endothelial cell by NF-kappaB-dependent pathway and reduce rat
myocardial damages incurred by ischemia and reperfusion in vivo. FEBS Lett. 2006 Feb
20;580(5):1391-7. Epub 2006 Jan 26. [12] Zhao QW, et al, Estrogenic activity and its mechanism
of ethanol extract from black soybean Zhongguo Zhong Yao Za Zhi. 2006 May;31(10):825-8. [13]
Inagaki S, et al, Isolation of tryptophol as an apoptosis-inducing component of vinegar produced
from boiled extract of black soybean in human monoblastic leukemia U937 cells. Biosci
Biotechnol Biochem. 2007 Feb;71(2):371-9. Epub 2007 Feb 7. [14] Black soya 'cuts diabetes risk'
BBC NEWS: 2007/02/26 10:23:23
cholesterol-lowering. Now, a recent animal study in Korea suggested that
intake of black soya beans could also benefit high cholesterol and may
help prevent diabetes. In this animal study, the group eating black soya
prevented weight gain and improved cholesterol levels. This finding can
be beneficial to diabetes. It is because the key problem in Type 2
diabetes is the impairment of insulin action, mainly as a result of excess
abdominal adipose tissue - so loss of weight is believed to benefit Type 2
diabetes. [14]
In fact, a while ago, Japanese researchers found black soybean had an
inhibitory effect of black soybeans on low density lipoprotein (LDL)
oxidation. The extract from black soybean also had a longer LDL
oxidation lag time than that from yellow soybean. [9]
Black soya bean (soybean) is rich in antioxidants.
Black soybean [Glycine max (L.) Merr.] has been used as a health food
and herb in China for hundreds of years. [1] Several studies have
demonstrated that the daily intakes of soy foods were associated with a
reduced cardiovascular risk. [9]
Researchers from Japan found black soybean seed coat contained a
variety of procyanidins, And, they showed high radical-scavenging
activities of these procyanidins in test-tube studies. [2] While researchers
from Korea considered that the seed coat of black soybean was a good
source of anthocyanin pigments such as cyanidin-3-glucoside and
delphinidin-3-glucoside. [3]
What are other potential benefits of eating black soya
bean (soybean)?
Eating black soya bean may reduce the risk of cancer and heart
diseases.
Korean researchers showed that anthocyanins isolated from black
soybean seed coat inhibited TNF-alpha-induced vascular cell adhesion
molecule-1, intracellular adhesion molecule-1, and cyclooxygenase-2
levels. Further, anthocyanins protected myocardiac injury from
ischemia-reperfusion in rats. Thus, anthocyanins from black soybean
seed coat benefit conditions like cardiovascular disorders. [11]
Researchers from Taiwan extracted a polysaccharide from the black
soybean. They found that this polysaccharide indirectly inhibited
proliferation and induced differentiation of human leukemic U937 cells via
activation of mononuclear cells in the study. [1]
Researchers found tryptophol from black soybean vinegar could inhibit
the proliferation of human monoblastic leukemia U937 cells by inducing
apoptosis via a pathway involving caspase-8 followed by caspase-3,
without affecting normal lymphocytes. [13]
Researchers from Taiwan noticed the promotion of myelopoiesis by an
active polysaccharide of black soybean in a study of murine spleen cells.
They also found that oral administration of that active polysaccharide of
black soybean in mice restored the leukocyte counts reduced by total
body-irradiation and 5-fluorouracil (5-FU) treatment. [6]
Eating black soya bean may enhance pregnancy.
Chinese researchers demonstrated the estrogenic activities of an
ethanol extract of black soybean. They found that the ethanol extract of
black soybean stimulated the growth of MCF-7 cells and increased the
expression of estrogen receptor-responsive gene in their study. [12] A
clinical study of 36 patients in Japan demonstrated that intake of black
soybean powder for six months improved ovulation and pregnancy. [10]
Black soya bean may have anti-fungi, anti-viral activities.
Hong Kong researchers isolated a monomeric protein, with a molecular
mass of 25 kDa and an N-terminal sequence resembling a segment of
chitin synthase from the seeds of the black soybean Glycine soja. This
protein, glysojanin, demonstrated potent antifungal activity against the
fungi Fusarium oxysporum and Mycosphaerella arachidicola. It also
inhibited HIV-1 reverse transcriptase in test-tubes. [5]
Japanese researchers found significant antiviral activities of a hot-water
black soybean extract in a test-tube study. This black soybean extract
showed significant antiviral activity against human adenovirus type 1 and
coxsackievirus B1 in a dose-dependent manner, [4]
ALL RIGHTS RESERVED ZHION 2007. THIS REFERENCE IS FOR YOUR REFERENCE ONLY.
CONSULT WITH YOUR DOCTOR FOR ANY QUESTIONS. [1] Liao HF et al, Isolation and
characterization of an active compound from black soybean [Glycine max (L.) Merr.] and its effect
on proliferation and differentiation of human leukemic U937 cells. Anticancer Drugs. 2001
Nov;12(10):841-6. [2] Takahata Y, et al, Highly polymerized procyanidins in brown soybean seed
coat with a high radical-scavenging activity. J Agric Food Chem. 2001 Dec;49(12):5843-7. [3]
Choung MG, et al, Isolation and determination of anthocyanins in seed coats of black soybean
(Glycine max (L.) Merr.). J Agric Food Chem. 2001 Dec;49(12):5848-51. [4] Yamai M, et al,
Antiviral activity of a hot water extract of black soybean against a human respiratory illness virus.
Biosci Biotechnol Biochem. 2003 May;67(5):1071-9. [5] Ngai PH, Ng TB. Purification of
glysojanin, an antifungal protein, from the black soybean Glycine soja. Biochem Cell Biol. 2003
Dec;81(6):387-94. [6] Liao HF, et al, A novel polysaccharide of black soybean promotes
myelopoiesis and reconstitutes bone marrow after 5-flurouracil- and irradiation-induced
myelosuppression. Life Sci. 2005 Jun 10;77(4):400-13. Epub 2005 Feb 25. [9] Takahashi R, et al,
Antioxidant activities of black and yellow soybeans against low density lipoprotein oxidation. J
Agric Food Chem. 2005 Jun 1;53(11):4578-82. [10] Kohama T, et al, The effect of soybeans on
the anovulatory cycle. J Med Food. 2005 Winter;8(4):550-1. [11] Kim HJ, et al, Anthocyanins from
soybean seed coat inhibit the expression of TNF-alpha-induced genes associated with
ischemia/reperfusion in endothelial cell by NF-kappaB-dependent pathway and reduce rat
myocardial damages incurred by ischemia and reperfusion in vivo. FEBS Lett. 2006 Feb
20;580(5):1391-7. Epub 2006 Jan 26. [12] Zhao QW, et al, Estrogenic activity and its mechanism
of ethanol extract from black soybean Zhongguo Zhong Yao Za Zhi. 2006 May;31(10):825-8. [13]
Inagaki S, et al, Isolation of tryptophol as an apoptosis-inducing component of vinegar produced
from boiled extract of black soybean in human monoblastic leukemia U937 cells. Biosci
Biotechnol Biochem. 2007 Feb;71(2):371-9. Epub 2007 Feb 7. [14] Black soya 'cuts diabetes risk'
BBC NEWS: 2007/02/26 10:23:23
Popular
Supplements
Acetyl-L Carnitine
Acidophilus
Almond
Bladderwrack
Bilberry
Chromium
CLA
Cod Liver Oil
Coenzyme Q
Colostrum
Dandelion
EGCG
Echinacea
Eleuthero
Ellagic Acid
Eve. Primrose Oil
Fish Oil
Flaxseed
Garlic
Ginger
Ginseng
Ginkgo Biloba
Glucosamine
Gotu Kola
Guar Gum
Hyaluronic acid
Lecithin
Lycopene
Milk Thistle
Nattokinase
Passion Flower
Probiotics
Policosanol /
Polycosanol
Pycnogenol
Reishi / Lingzhi
Resveratrol
Rhodiola
Royal Jelly
Stevia
Whey
Xylitol
More Supplements
Supplements
Acetyl-L Carnitine
Acidophilus
Almond
Bladderwrack
Bilberry
Chromium
CLA
Cod Liver Oil
Coenzyme Q
Colostrum
Dandelion
EGCG
Echinacea
Eleuthero
Ellagic Acid
Eve. Primrose Oil
Fish Oil
Flaxseed
Garlic
Ginger
Ginseng
Ginkgo Biloba
Glucosamine
Gotu Kola
Guar Gum
Hyaluronic acid
Lecithin
Lycopene
Milk Thistle
Nattokinase
Passion Flower
Probiotics
Policosanol /
Polycosanol
Pycnogenol
Reishi / Lingzhi
Resveratrol
Rhodiola
Royal Jelly
Stevia
Whey
Xylitol
More Supplements
 |  |  |  |