| Flaxseed Lignans Health Benefits March 20, 2007. |
Bhathena SJ and Velasquez MT from US Department of
Agriculture, MD, reported that Nutritional intervention studies
performed in animals and humans suggest that the ingestion
of flaxseed rich in lignans (matairesinol and
secoisolariciresinol) improves glucose control and insulin
resistance in their review article. [1] Lignans appear to act
through various mechanisms that modulate pancreatic insulin
secretion or through antioxidative actions. They may also act
via estrogen receptor-mediated mechanisms. The diversity of
cellular actions of flaxseed lignans supports their possible
beneficial effects on various chronic diseases, especially
diabetes. [1-5]
Secoisolariciresinol diglucoside (SDG) is metabolized to
secoisolariciresinol (SECO), enterodiol (ED), and
enterolactone (EL) in the body. These metabolites, vitamin E
and SDG showed antioxidant activities in a study using
chemiluminescence of zymosan-activated polymorphonuclear
leukocytes. Prasad K. from University of Saskatchewan found
the highest antioxidant activity with secoisolariciresinol and
enterodiol and lowest with vitamin E. [3] Dr. Prasad also
found that secoisolariciresinol diglucoside (SDG) prevented
or delayed the development of diabetes in a study of 26
diabetic fatty female rats. Incidence of diabetes was 100% in
untreated and 20% in secoisolariciresinol diglucoside
-treated diabetic rats by the age of 72 days. [2]
Diabetes was associated with an increase in oxidative stress
as suggested by an increase in serum malondialdehyde, and
associated with an increase in serum total cholesterol and
triglycerides and glycated hemoglobin A. Diabetic rats
treated with secoisolariciresinol diglucoside that did not
develop diabetes by 70 days of age had no increase in
oxidative stress, serum total cholesterol, and glycated
hemoglobin. [2]
Benefits of Flaxseed Meal
Benefits of Flaxseed Oil
ALL RIGHTS RESERVED ZHION 2007 [1] Bhathena SJ, et al, Beneficial role of dietary
phytoestrogens in obesity and diabetes. Am J Clin Nutr. 2002 Dec;76(6):1191-201. [2]
Prasad K. Secoisolariciresinol diglucoside from flaxseed delays the development of type
2 diabetes in Zucker rat. J Lab Clin Med. 2001 Jul;138(1):32-9. [3] Prasad K. Antioxidant
Activity of Secoisolariciresinol Diglucoside-derived Metabolites, Secoisolariciresinol,
Enterodiol, and Enterolactone. Int J Angiol. 2000 Oct;9(4):220-225. [4] Prasad K.
Oxidative stress as a mechanism of diabetes in diabetic BB prone rats: effect of
secoisolariciresinol diglucoside (SDG). Mol Cell Biochem. 2000 Jun;209(1-2):89-96. [5]
Prasad K, et al, Protective effect of secoisolariciresinol diglucoside against
streptozotocin-induced diabetes and its mechanism. Mol Cell Biochem. 2000
Mar;206(1-2):141-9.
Agriculture, MD, reported that Nutritional intervention studies
performed in animals and humans suggest that the ingestion
of flaxseed rich in lignans (matairesinol and
secoisolariciresinol) improves glucose control and insulin
resistance in their review article. [1] Lignans appear to act
through various mechanisms that modulate pancreatic insulin
secretion or through antioxidative actions. They may also act
via estrogen receptor-mediated mechanisms. The diversity of
cellular actions of flaxseed lignans supports their possible
beneficial effects on various chronic diseases, especially
diabetes. [1-5]
Secoisolariciresinol diglucoside (SDG) is metabolized to
secoisolariciresinol (SECO), enterodiol (ED), and
enterolactone (EL) in the body. These metabolites, vitamin E
and SDG showed antioxidant activities in a study using
chemiluminescence of zymosan-activated polymorphonuclear
leukocytes. Prasad K. from University of Saskatchewan found
the highest antioxidant activity with secoisolariciresinol and
enterodiol and lowest with vitamin E. [3] Dr. Prasad also
found that secoisolariciresinol diglucoside (SDG) prevented
or delayed the development of diabetes in a study of 26
diabetic fatty female rats. Incidence of diabetes was 100% in
untreated and 20% in secoisolariciresinol diglucoside
-treated diabetic rats by the age of 72 days. [2]
Diabetes was associated with an increase in oxidative stress
as suggested by an increase in serum malondialdehyde, and
associated with an increase in serum total cholesterol and
triglycerides and glycated hemoglobin A. Diabetic rats
treated with secoisolariciresinol diglucoside that did not
develop diabetes by 70 days of age had no increase in
oxidative stress, serum total cholesterol, and glycated
hemoglobin. [2]
Benefits of Flaxseed Meal
Benefits of Flaxseed Oil
ALL RIGHTS RESERVED ZHION 2007 [1] Bhathena SJ, et al, Beneficial role of dietary
phytoestrogens in obesity and diabetes. Am J Clin Nutr. 2002 Dec;76(6):1191-201. [2]
Prasad K. Secoisolariciresinol diglucoside from flaxseed delays the development of type
2 diabetes in Zucker rat. J Lab Clin Med. 2001 Jul;138(1):32-9. [3] Prasad K. Antioxidant
Activity of Secoisolariciresinol Diglucoside-derived Metabolites, Secoisolariciresinol,
Enterodiol, and Enterolactone. Int J Angiol. 2000 Oct;9(4):220-225. [4] Prasad K.
Oxidative stress as a mechanism of diabetes in diabetic BB prone rats: effect of
secoisolariciresinol diglucoside (SDG). Mol Cell Biochem. 2000 Jun;209(1-2):89-96. [5]
Prasad K, et al, Protective effect of secoisolariciresinol diglucoside against
streptozotocin-induced diabetes and its mechanism. Mol Cell Biochem. 2000
Mar;206(1-2):141-9.
MAJOR NUTRIENT
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PhytoChemicals
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Acidophilus
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Beet
black cohosh
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Maca
Maitake
Mango
Mangosteen
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Melatonin
Milk Thistle
Mistletoe
N-Acetylcysteine
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Nectarines
Octacosanol
Olive Oil
Omegic Fatty
Acids
Onion
Orange
Oregon Grape
Pantethine
Papaya
Passion Flower
PEANUT
Peach
Peony
Pepper
Peppermint
Persimmons
Phellinus linteus
Phosphatidyl
serine
Phyllanthus
Potato
Plum
Pomegranate
Probiotics
Policosanol /
Polycosanol
Propolis
Pumpkin
Pycnogenol
Pyruvate
Quercetin
Quince
Radish
Red Clover
Red Yeast Rice
Reishi / Lingzhi
Resveratrol
Rhodiola
Rhubarb
Rice Bran Oil
Rosemary
Royal Jelly
Rutin
S-adenosyl-L-
methionine
Saffron
Saw Palmetto
Schisandra
Selenium
Spinach
Spirulina
Squash
Stinging Nettle
St John Wort
Strawberry
Sweet Potatoes
Taxifolin
Tea Tree Oil
Turmeric [Curry]
Tyrosine
Shark Cartilage
Soy
Stevia
Valerian
Vitamin D
Vitex
Walnuts
Watermelon
Whey
Wild Yam
Witch Hazel
Wormwood
Xylitol
Yarrow
Yohimbe
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5-Hydroxytrpto
phan
Food Industry
Organic Label
HOME
Herb Side Effect
Blood Pressure
Lowering Herbs
Cholesterol
Lowering Herbs
Supplements for
Cadiovascular
Diseases
DIET.
SUPPLEMENT
PhytoChemicals
Antioxidants
A-Z Health Foods,
Products
Acetyl-L Carnitine
Acidophilus
Alfalfa
Almond
Aloe vera
Andrographis
Aniseed
Apple
Arnica
Ashwagandha
Asian Pears
Asparagus
Astaxanthin,
Astragulus
Artichoke
Avena sativa
Avocados
Barley
Banana
Basil
Beet
black cohosh
Bladderwrack
Blackberry
Black Currant
Bloodroot
Blueberry
Bilberry
Bitter Melon
Borage Seed Oil
Boswellia
Black Soya Bean
Broccoli
Bromelain
Brown Seaweed
Brussels Sprout
Butterbur
Burdock
Cabbage
Cactus
Caffeine
Calcium
Calendula
Canola oil
Cauliflower
Cat's Claw
Cayenne
Celadrin
Celery
Chamomile
Chaparral
Cherry
Chokeberry
Chondroitin
Chitosan
Chlorophyll
Chromium
Cinnamon
CLA
Cocoa
Cod Liver Oil
Coenzyme Q
Coffee
Comfrey
Conj. Linoleic Acid
Colostrum
Colloidal Silver
Cordyceps
Corn
Cranberry
Creatine
Curcumin
Damiana
Dandelion
Danggui_Buxue
Devil's Claw
DHEA
Dill
Dong Quai
EGCG
Echinacea
Eleuthero
Ellagic Acid
Eucalyptus G.
Eve. Primrose Oil
Falcarinol
Fennel
Fenugreek
Feverfew
Folate
Fish Oil
Flaxseed Meal
Flaxseed /Linseed
Garcinia C.
Garlic
Galangal
Ghrelin
Ginger
Ginseng
Ginseng/Ginkgo
Ginkgo Biloba
Glucosamine
Goldenseal
Gotu Kola
GRAPE SEED
EXTRACT
Green Coffee Bean
Green Tea
Growth Hormone
Stimulants
Goldenseal
Guar Gum
Guggul
Gymnema
Hawthorn
Hoodia
Hop
Horse Chestnut
Horsetail
Huperzine A
Hyaluronic acid
Isothiocyanates
Kava Kava
Kelp
L-arginine
Lavender
Lecithin
Lemon balm
Licorice
Lingonberry
Lutein
Lycopene
Maca
Maitake
Mango
Mangosteen
Marshmallow
Melatonin
Milk Thistle
Mistletoe
N-Acetylcysteine
Nattokinase
Nectarines
Octacosanol
Olive Oil
Omegic Fatty
Acids
Onion
Orange
Oregon Grape
Pantethine
Papaya
Passion Flower
PEANUT
Peach
Peony
Pepper
Peppermint
Persimmons
Phellinus linteus
Phosphatidyl
serine
Phyllanthus
Potato
Plum
Pomegranate
Probiotics
Policosanol /
Polycosanol
Propolis
Pumpkin
Pycnogenol
Pyruvate
Quercetin
Quince
Radish
Red Clover
Red Yeast Rice
Reishi / Lingzhi
Resveratrol
Rhodiola
Rhubarb
Rice Bran Oil
Rosemary
Royal Jelly
Rutin
S-adenosyl-L-
methionine
Saffron
Saw Palmetto
Schisandra
Selenium
Spinach
Spirulina
Squash
Stinging Nettle
St John Wort
Strawberry
Sweet Potatoes
Taxifolin
Tea Tree Oil
Turmeric [Curry]
Tyrosine
Shark Cartilage
Soy
Stevia
Valerian
Vitamin D
Vitex
Walnuts
Watermelon
Whey
Wild Yam
Witch Hazel
Wormwood
Xylitol
Yarrow
Yohimbe
Yucca
5-Hydroxytrpto
phan
Food Industry
Organic Label
HOME
Herb Side Effect
Blood Pressure
Lowering Herbs
Cholesterol
Lowering Herbs
Supplements for
Cadiovascular
Diseases
| Flaxseed Why is flaxseed meal getting popular? What is its benefits? Flaxseed meal was found to be more beneficial on some chronic conditions such as high triglycerides and liver steatosis than soy protein meal, in a study of rats. Flaxseed or Flaxseed oil, which one offers better health benefits? Flaxseed oil alone in human subjects had no effects on the lipid profiles in some studies. Why are lignans so important in flaxseed? ingestion of flaxseed rich in lignans (matairesinol and secoisolariciresinol) improves glucose control and insulin resistance. What are the health benefits of flaxseed oil? Flaxseed oil has been shown benefits on lowering heart diseases by reducing cholesterol levels, high blood pressure and slowing down atherosclerosis. |