Fennel (Foeniculum vulgare) is an herb that is native to the Mediterranean region, but is currently cultivated in
most temperate areas. The constituent oils and extracts of Fennel Seed have been shown to possess
considerable benefits in various areas: inflammation, asthma, indigestion, hirsutism and colic. It is also an
anti-oxidant, anti-bacterial  and hepato-protective agent. And, researchers use it to develop tea to clear the
throat and repel mosquitoes.
RESEARCH FINDINGS

Researchers have evaluated the potential effects of fennel on
various health conditions, and fennel appears to have a wide
range of health benefits:

ANTI-BACTERIAL / ANTIMICROBIAL GROWTH
Dadalioglu I et al , Mustafa Kemal University, Turkey, found that
fennel exhibited a very strong antibacterial activity against
bacteria Escherichia coli O157:H7, Listeria monocytogenes,
Salmonella typhimurium, and Staphylococcus aureus in a vitro
study.
[J Agric Food Chem. 2004 Dec 29;52(26):8255-60]. Lo Cantore P
et al, Universita di Napoli "Federico II", Italy, even suggested to use it as
natural bactericide for the control of bacterial diseases of plants and for
seed treatment, in particular, in organic agriculture. [J Agric Food Chem.
2004 Dec 29;52(26):7862-7866].

Singh G et al, DDU Gorakhpur University, India, studied
Foeniculum vulgare, Pimpinella anisum and Seseli indicum for
antibacterial activity against eight pathogenic bacteria, causing
infections in the human body. They concluded that it is effective
when compared with standard antibiotics, at a very low
concentration.
[Phytother Res. 2002 Nov;16(7):680-2].

Kwon YS et al, Kangwon National University, Korea, found a
phenyl propanoid derivative, dillapional(1) be a antimicrobial
principle of the stems of Foeniculum vulgare.
[Arch Pharm Res. 2002
Apr;25(2):154-7]
.

REPEL MOSQUITOES
Kim SI et al, Seoul National University, Korea, incorporated fennel
oil into aerosol and cream products to repel mosquitoes.
[Pest
Manag Sci. 2004 Nov;60(11):1125-30; J Agric Food Chem. 2002 Nov
20;50(24):6993-6].

ANTI-OXIDANT ACTIVITIES
Satyanarayana S et al, Andhra University, India, suggested daily
use of Foeniculum vulgare in various forms is very common in
India and their study revealed strong antioxidant activity of the
extracts that was superior to known antioxidant ascorbic acid and
indicate their intake may be beneficial as food additives.
[J Herb
Pharmcother. 2004;4(2):1-10]

Parejo I et al, Universitat de Barcelona, Spain isolated and
identified of the nonvolatile antioxidant compounds from fennel
(Foeniculum vulgare Mill.) waste: in fennel: 3-caffeoylquinic acid,
4-caffeoylquinic acid, 1,5-O-dicaffeoylquinic acid, rosmarinic acid,
eriodictyol-7-O-rutinoside, quercetin-3-O-galactoside,
kaempferol-3-O-rutinoside, and kaempferol-3-O-glucoside. And,
these compounds exhibited a strong antiradical scavenging
activity.
[J Agric Food Chem. 2004 Apr 7;52(7):1890-7]

ANTI-INFLAMMATORY ACTIVIES
Choi EM et al, Yonsei University, Korea, suggested that oral
administration (200 mg/kg) of Foeniculum vulgare fruit methanolic
extract exhibited inhibitory effects against acute and subacute
inflammatory diseases and type IV allergic reactions and showed
a central analgesic effect.
[Fitoterapia. 2004 Sep;75(6):557-65].

THROAT CLEARING
Puodziuniene G et al, Kaunas University of Medicine, Lithuania,
develop of throat clearing herbal teas using fennel as one of the
active ingredients.
[Medicina (Kaunas). 2004;40(8):762-7]

ASTHMA
Haggag EG et al, Ain Helwan, Egypt, developed an water extract
of a mixture of eight herbs (chamomile, saffron, anise, fennel,
caraway, licorice, cardamom and black seed). And, he found that
this herbal water-extract inhibited histamine released from
chemically- and immunologically-induced cells by 81% and 85%.
And, the clinical results showed significant improvements of sleep
discomfort, cough frequency and cough intensity.
[J Herb
Pharmcother. 2003;3(4):41-54]

DIGESTION
Ramakrishna Rao R et al, Central Food Technological Research
Institute, India, examined in vitro influence of 14 individual spices
(curcumin, capsaicin, piperine, garlic, onion, ginger, mint,
coriander, cumin, ajowan, fennel, fenugreek, mustard, and
asafoetida) on the activities of digestive enzymes of rat pancreas
and small intestine by including them in the reaction mixture at
two different concentrations. The study suggested that spices
had an overall digestive stimulation.
[Nahrung. 2003
Dec;47(6):408-12]

ANTI-HIRSUTISM
Idiopathic hirsutism is the occurrence of excessive male pattern
hair growth in women who have a normal ovulatory menstrual
cycle and normal levels of serum androgens. Javidnia K et al,
Shiraz University of Medical Sciences, Iran evaluated the clinical
response of idiopathic hirsutism to topical Fennel extract. They
treated 38 patients with creams containing 1%, 2% of Fennel
extract and placebo in a double bind study. They then measured
hair diameter was measured and rate of growth. They found that
the mean values of hair diameter reduction was 7.8%, 18.3% and
-0.5% for patients receiving the creams containing 1%, 2% and
0% (placebo) respectively.
[Phytomedicine. 2003;10(6-7):455-8]

INFANTILE COLIC
Colic is a condition in which an infant cries for at least three hours
a day, for at least three days a week and continues for more than
three weeks. Causes of colic may include food allergies, formula
intolerance (such as lactose intolerance), excessive gas
formation, or intestinal cramping. Alexandrovich I et al, St.
Petersburg Medical Academy of Postdoctoral Education, Russia
randomly assigned 121 infants with colic to receive 5 to 20 ml of a
0.1% fennel seed oil emulsion or placebo up to four times per day
for one week. Acording to the Wessel criteria, the use of fennel oil
emulsion eliminated colic in 65% (40/62) of infants in the
treatment group, which was significantly better than 23.7%
(14/59) of infants in the control group (P < 0.01).
[Altern Ther
Health Med. 2003 Jul-Aug;9(4):58-61]

HEPATO-PROTECTIVE EFFECT
Ozbek H et al, Yuzuncu Yil University, Turkey, studied the
hepato-protective activity of Foeniculum vulgare (fennel) essential
oil (FEO) using carbon tetrachloride (CCl(4)) induced liver injury
model in rats. They found that FEO inhibited the hepatotoxicity
produced by acute CCl(4) administration with evidence of
decreased levels of serum aspartate aminotransferase (AST),
alanine aminotransferase (ALT), alkaline phosphatase (ALP) and
bilirubin.
[ Fitoterapia. 2003 Apr;74(3):317-9].

CONCLUSION
Fennel appears to have a wide range of health benefits, based
on several foundamental studies. More clinical studies are needed
to confirm the health claim
s.

The information above is for your reference only. If you have any
questions, please, consult with your medical doctor immediately. ALL
RIGHT RESERVED 2008 zhion.
FENNEL HEALTH BENEFITS
zhion@zhion.com       2008
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