NEW CANCER TEST:
OPTICAL STRETCHER TEST
last updated April 19, 2007
Professor Josef Käs and Dr Jochen Guck at The
University of Leipzig are developing a new test for
cancer. It is the first time to use a physical
characteristic of each cell ' its stretchiness or
elasticity' instead of its biological make-up, to
decide whether or not it's cancerous. Cancer cells
de-differentiate and loss the rigid cytoskeleton
which holds them in shape. Consequently, they
are more elastic or 'stretchable' than normal cells.
To a certain extent, this method can also give the
stage of the cancer from the elasticity of the cells.
The softer the cancer cells, the more likely they are
traveling to other locations in the body-
metastases. Traditionally, doctors need to check
nearby lymph nodes for cancer cells to determine
if metastases have occurred or not. Besides, this
method needs only 50 tumor cells in a sample for
the optical stretcher to diagnose cancer,
compared to traditional methods which require
10,000 to 100,000 cells. Thus, their method is
much sensitive than current methods available.
Finally, their method can test as many as 3,600
cells per minute, it can be used in the clinical
diagnosis of cancer.
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References
Institute of Physics conference Physics 2005 in
Warwick, April 12, 2005. Scientists announce
world's most sensitive cancer test, Innovations
Report.com, April 12, 2005