Researchers from Kao Corporation, Tokyo, Japan:

Chlorogenic acids (CGA) in green coffee bean extract (GCE) reduce blood
pressure in spontaneously hypertensive rats and humans. The researchers
examined the blood pressure-lowering effect and safety of CGA in patients with
mild hypertension through a placebo-controlled, randomized clinical trial.
Subjects (n = 28) were randomized to receive treatment with CGA (140 mg/day)
from GCE or placebo. They found that blood pressure (systolic and diastolic)
decreased significantly during the ingestion period in the CGA group but not the
placebo group. They concluded that CGA from GCE is effective in decreasing
blood pressure and safe for patients with mild hypertension. [1]


[1] The blood pressure-lowering effect and safety of chlorogenic acid from green
coffee bean extract in essential hypertension.
green coffee bean extract
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