Zhion.com
a site to share health knowledge
a site to share health knowledge
 |  |  |  |
Acidophilus is lactic acid-producing bacteria. In general, lactobacillus
acidophilus is considered to possess health-promoting attributes. It passes
through the intestine benefiting host's physiology.
Lactobacillus acidophilus is widely used as live supplement. The potential
benefits of lactobacillus acidophilus in fermented dairy products are
dependent on their survival during manufacture and storage. Lactobacillus
acidophilus is increasingly used in food and pharmaceutical applications to
balance disturbed intestinal microflora and related dysfunction of the
human gastrointestinal tract. Lactobacillus acidophilus has been reported
to provide excellent therapeutic benefits. [1]
HOW DOES LACTOBACILLUS ACIDOPHILUS BENEFIT OUR BODY
HEALTH?
1.INFECTION PREVENTION
Lactobacillus acidophilus may have importance in the prevention and
adjuvant therapy of new-born and childhood enteritis, certain inflammations
and antibiotic associated diarrhoea. Administration of lactobacillus
acidophilus creates eubiosis between the human organism and the world of
bacteria assuring normal physiologic functions for the well-being of the
organism. [2,3]
Lactobacillus acidophilus adheres to Caco-2 and mucus-secreting HT-29
cell culture systems, produces antimicrobial compounds, and is amenable
to genetic manipulation and directed DNA introduction. Lactobacillus
acidophilus survives gastrointestinal tract transit in both healthy and
diseased populations.
A blend of probiotic strains containing lactobacillus acidophilus decreased
the incidence of pediatric diarrhea. Lactobacillus acidophilus led to a
significant decrease in levels of toxic amines in the blood of dialysis
patients with small bowel bacterial overgrowth. At adequate daily feeding
levels, Lactobacillus acidophilus may facilitate lactose digestion in
lactose-intolerant subjects. Further validation of the probiotic properties of
NCFM in humans and clarification of its mechanisms of probiotic action are
needed to better understand the role this strain might play in promoting
human health. [4]
The biological activity of lactobacillus acidophilus is due in part to their
ability to attach to enterocytes. This inhibits the binding of enteric
pathogens by a process of competitive exclusion, i.e. competition for
nutrients and adhesion sites. [3] Attachment of lactobacillus acidophilus to
cell surface receptors of enterocytes also initiates signalling events that
result in the synthesis of cytokines. Lactobacillus acidophilus also exerts an
influence on commensal micro-organisms by the production of organic
acids (e.g.lactic acids), hydrogen peroxide, antibiotic-like compounds and
bacteriocins. These substances inhibit growth of pathogens and also alter
the ecological balance of enteric commensals. [1]
Irritable Bowel Syndrome Although the cause of irritable bowel syndrome is
not known, one possibility is a disturbance in healthy intestinal bacteria.
Based on this theory, Lactobacillus acidophilus have been tried as a
treatment for IBS. Benefits were seen in three other small double-blind
trials as well, using Lactobacillus acidophilus. [5]
CANCER RISK LOWERING
Production of butyric acid lactobacillus acidophilus affects the turnover of
enterocytes and neutralizes the activity of dietary carcinogens, such as
nitrosamines, that are generated by the metabolic activity of commensal
bacteria in subjects consuming a high-protein diet. Therefore, inclusion of
lactobacillus acidophilus in fermented dairy products enhances their value
as better therapeutic functional foods. [1] A study has shown that
lactobacillus acidophilus inhibited aberrant crypt formation in mutagenized
rats, indicative of activity that could decrease the risk of colon cancer. [4]
CHOLESTEROL LOWERING
Lactobacillus acidophilus may be able to inhibit 3-hydroxy-3-methylglutaryl
CoA reductase (an enzyme for cholesterol biosynthesis) and promote the
excretion of dietary cholesterol in feces. Thus, lactobacillus acidophilus has
the benefit for high cholesterol [3]
IMMUNE RESPONSE
One study found that Lactobacillus acidophilus may improve the immune
response to vaccinations. 6
Sources and Commercial Supplements
Dairy products such as yogurt and kefir are good sources of acidophilus.
Supplements are widely available in powder, liquid, capsule, or tablet form.
Grocery stores and natural food stores both carry milk that contains live
acidophilus. Dosages of acidophilus are expressed in billions of organisms.
A typical daily dose should supply about 3 to 5 billion live organisms.
Acidophilus 4X6 Powder, Now, has 4 billion potency (2 billion lactobacillus
acidophilus) and 6 probiotic strains per serving (1/4 teaspoon; 700 mg).
Acidophilus 2 Billion, Now, has 2 billion potency (2 billion lactobacillus
acidophilus) per serving (1/2 teaspoon; 1 g). Mega Acidophilus, Natural
Factors, has 6 billion active cells (5.7 billion of L. rhamnosus and L.
acidophilus) and 200 mg of fructooligosaccharides (FOS) per serving.
Most acidophilus products require refrigerated for maintaining the potency.
The shelf-life is about 1-2 years.
This article is for your reference only. If you have any questions, please, consult with your doctor
immediately. All right reserved 2008 ZHION Do not copy nor transfer this article to other
websites.
[1] Kailasapathy K et al Survival and therapeutic potential of probiotic organisms with reference to
Lactobacillus acidophilus and Bifidobacterium spp. Immunol Cell Biol. 2000 Feb;78(1):80-8. [2]
Halmy C et al, The role of Lactobacillus acidophilus in the prevention and adjuvant therapy of
certain infectious diseases Orv Hetil. 1998 Sep 27;139(39):2313-8. [3] Mital BK et al,
Anticarcinogenic, hypocholesterolemic, and antagonistic activities of Lactobacillus acidophilus.
Crit Rev Microbiol. 1995;21(3):175-214. [4] Sanders ME et al, Invited review: the scientific basis of
Lactobacillus acidophilus NCFM functionality as a probiotic. J Dairy Sci. 2001 Feb;84(2):319-31. 5.
Halpern GM, Prindiville T, Blankenberg M, et al. Treatment of irritable bowel syndrome with Lacteol
Fort: a randomized, double-blind, cross-over trial. Am J Gastroenterol. 1996;91:1579–1585.
6. de Vrese M, Rautenberg P, Laue C, et al. Probiotic bacteria stimulate virus-specific neutralizing
antibodies following a booster polio vaccination. Eur J Nutr. 2004 Dec 1 [Epub ahead of print].
acidophilus is considered to possess health-promoting attributes. It passes
through the intestine benefiting host's physiology.
Lactobacillus acidophilus is widely used as live supplement. The potential
benefits of lactobacillus acidophilus in fermented dairy products are
dependent on their survival during manufacture and storage. Lactobacillus
acidophilus is increasingly used in food and pharmaceutical applications to
balance disturbed intestinal microflora and related dysfunction of the
human gastrointestinal tract. Lactobacillus acidophilus has been reported
to provide excellent therapeutic benefits. [1]
HOW DOES LACTOBACILLUS ACIDOPHILUS BENEFIT OUR BODY
HEALTH?
1.INFECTION PREVENTION
Lactobacillus acidophilus may have importance in the prevention and
adjuvant therapy of new-born and childhood enteritis, certain inflammations
and antibiotic associated diarrhoea. Administration of lactobacillus
acidophilus creates eubiosis between the human organism and the world of
bacteria assuring normal physiologic functions for the well-being of the
organism. [2,3]
Lactobacillus acidophilus adheres to Caco-2 and mucus-secreting HT-29
cell culture systems, produces antimicrobial compounds, and is amenable
to genetic manipulation and directed DNA introduction. Lactobacillus
acidophilus survives gastrointestinal tract transit in both healthy and
diseased populations.
A blend of probiotic strains containing lactobacillus acidophilus decreased
the incidence of pediatric diarrhea. Lactobacillus acidophilus led to a
significant decrease in levels of toxic amines in the blood of dialysis
patients with small bowel bacterial overgrowth. At adequate daily feeding
levels, Lactobacillus acidophilus may facilitate lactose digestion in
lactose-intolerant subjects. Further validation of the probiotic properties of
NCFM in humans and clarification of its mechanisms of probiotic action are
needed to better understand the role this strain might play in promoting
human health. [4]
The biological activity of lactobacillus acidophilus is due in part to their
ability to attach to enterocytes. This inhibits the binding of enteric
pathogens by a process of competitive exclusion, i.e. competition for
nutrients and adhesion sites. [3] Attachment of lactobacillus acidophilus to
cell surface receptors of enterocytes also initiates signalling events that
result in the synthesis of cytokines. Lactobacillus acidophilus also exerts an
influence on commensal micro-organisms by the production of organic
acids (e.g.lactic acids), hydrogen peroxide, antibiotic-like compounds and
bacteriocins. These substances inhibit growth of pathogens and also alter
the ecological balance of enteric commensals. [1]
Irritable Bowel Syndrome Although the cause of irritable bowel syndrome is
not known, one possibility is a disturbance in healthy intestinal bacteria.
Based on this theory, Lactobacillus acidophilus have been tried as a
treatment for IBS. Benefits were seen in three other small double-blind
trials as well, using Lactobacillus acidophilus. [5]
CANCER RISK LOWERING
Production of butyric acid lactobacillus acidophilus affects the turnover of
enterocytes and neutralizes the activity of dietary carcinogens, such as
nitrosamines, that are generated by the metabolic activity of commensal
bacteria in subjects consuming a high-protein diet. Therefore, inclusion of
lactobacillus acidophilus in fermented dairy products enhances their value
as better therapeutic functional foods. [1] A study has shown that
lactobacillus acidophilus inhibited aberrant crypt formation in mutagenized
rats, indicative of activity that could decrease the risk of colon cancer. [4]
CHOLESTEROL LOWERING
Lactobacillus acidophilus may be able to inhibit 3-hydroxy-3-methylglutaryl
CoA reductase (an enzyme for cholesterol biosynthesis) and promote the
excretion of dietary cholesterol in feces. Thus, lactobacillus acidophilus has
the benefit for high cholesterol [3]
IMMUNE RESPONSE
One study found that Lactobacillus acidophilus may improve the immune
response to vaccinations. 6
Sources and Commercial Supplements
Dairy products such as yogurt and kefir are good sources of acidophilus.
Supplements are widely available in powder, liquid, capsule, or tablet form.
Grocery stores and natural food stores both carry milk that contains live
acidophilus. Dosages of acidophilus are expressed in billions of organisms.
A typical daily dose should supply about 3 to 5 billion live organisms.
Acidophilus 4X6 Powder, Now, has 4 billion potency (2 billion lactobacillus
acidophilus) and 6 probiotic strains per serving (1/4 teaspoon; 700 mg).
Acidophilus 2 Billion, Now, has 2 billion potency (2 billion lactobacillus
acidophilus) per serving (1/2 teaspoon; 1 g). Mega Acidophilus, Natural
Factors, has 6 billion active cells (5.7 billion of L. rhamnosus and L.
acidophilus) and 200 mg of fructooligosaccharides (FOS) per serving.
Most acidophilus products require refrigerated for maintaining the potency.
The shelf-life is about 1-2 years.
This article is for your reference only. If you have any questions, please, consult with your doctor
immediately. All right reserved 2008 ZHION Do not copy nor transfer this article to other
websites.
[1] Kailasapathy K et al Survival and therapeutic potential of probiotic organisms with reference to
Lactobacillus acidophilus and Bifidobacterium spp. Immunol Cell Biol. 2000 Feb;78(1):80-8. [2]
Halmy C et al, The role of Lactobacillus acidophilus in the prevention and adjuvant therapy of
certain infectious diseases Orv Hetil. 1998 Sep 27;139(39):2313-8. [3] Mital BK et al,
Anticarcinogenic, hypocholesterolemic, and antagonistic activities of Lactobacillus acidophilus.
Crit Rev Microbiol. 1995;21(3):175-214. [4] Sanders ME et al, Invited review: the scientific basis of
Lactobacillus acidophilus NCFM functionality as a probiotic. J Dairy Sci. 2001 Feb;84(2):319-31. 5.
Halpern GM, Prindiville T, Blankenberg M, et al. Treatment of irritable bowel syndrome with Lacteol
Fort: a randomized, double-blind, cross-over trial. Am J Gastroenterol. 1996;91:1579–1585.
6. de Vrese M, Rautenberg P, Laue C, et al. Probiotic bacteria stimulate virus-specific neutralizing
antibodies following a booster polio vaccination. Eur J Nutr. 2004 Dec 1 [Epub ahead of print].
Popular
Supplements
Acetyl-L Carnitine
Acidophilus
Bladderwrack
Bilberry
Chromium
CLA
Cod Liver Oil
Coenzyme Q
Colostrum
Dandelion
EGCG
Echinacea
Eleuthero
Ellagic Acid
Eve. Primrose Oil
Fish Oil
Flaxseed
Garlic
Ginger
Ginseng
Ginkgo Biloba
Glucosamine
Gotu Kola
Guar Gum
Hyaluronic acid
Lecithin
Lycopene
Milk Thistle
Nattokinase
Passion Flower
Probiotics
Policosanol /
Polycosanol
Pycnogenol
Reishi / Lingzhi
Resveratrol
Rhodiola
Royal Jelly
Stevia
Whey
Xylitol
Supplements
Acetyl-L Carnitine
Acidophilus
Bladderwrack
Bilberry
Chromium
CLA
Cod Liver Oil
Coenzyme Q
Colostrum
Dandelion
EGCG
Echinacea
Eleuthero
Ellagic Acid
Eve. Primrose Oil
Fish Oil
Flaxseed
Garlic
Ginger
Ginseng
Ginkgo Biloba
Glucosamine
Gotu Kola
Guar Gum
Hyaluronic acid
Lecithin
Lycopene
Milk Thistle
Nattokinase
Passion Flower
Probiotics
Policosanol /
Polycosanol
Pycnogenol
Reishi / Lingzhi
Resveratrol
Rhodiola
Royal Jelly
Stevia
Whey
Xylitol
ARTICLES IN THIS WEB SITE IS FOR YOUR REFERENCE ONLY. IF YOU HAVE ANY QUESTION, YOU SHOULD CONSULT WITH YOUR
DOCTOR IMMEDIATELY. ALL RIGHTS RESERVED 2008. DO NOT COPY NOR TRANSFER ARTICLES TO OTHER WEBSITES NOR OTHER
FORMS OF PUBLICATIONS. ARTICLE INDEX
DOCTOR IMMEDIATELY. ALL RIGHTS RESERVED 2008. DO NOT COPY NOR TRANSFER ARTICLES TO OTHER WEBSITES NOR OTHER
FORMS OF PUBLICATIONS. ARTICLE INDEX
 | |  | |  | |  | |  | |  | |  |