Oligofructose
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Oligofructose (OF), comprised of fructose oligomers with a terminal glucose
unit, is a family of oligosaccharides derived from the hydrolysis of inulin. [3]
Its degree of polymerization (DP) is less than or equal to 10. Oligofructose is
not digested in the upper gastrointestinal tract; therefore, it has a reduced
caloric value. [1]
Consumption of OF in animals and humans increases colonic bifidobacteria
levels. [3] It does not lead to a rise in serum glucose or stimulate insulin
secretion. [1]
Oligofructose has a sweet, pleasant flavor and is highly soluble. It can be used
to fortify foods with fiber without contributing any deleterious organoleptic
effects, to improve the flavor and sweetness of low calorie foods and to
improve the texture of fat-reduced foods. [1]
Researchers from Equipe Stress Métabolique et Micronutriments, France, found
supplementation with inulin-type fructans in rats is efficient against fructose
induced hypertension and that effects are most pronounced for long-chain
inulin and oligofructose-enriched inulin. [4]
Side Effects of Oligofructose
Oligofructose overload at 17 g/kg of body weight represented a relatively mild
laminitis model in cattle, as demonstrated by a reasonably quick recovery from
systemic as well as orthopedic signs.
Source
[1] Inulin and Oligofructose: What Are They, Journal of Nutrition.
1999;129:1402S-1406S.
[2] Danscher AM, Enemark JM, Telezhenko E, Capion N, Ekstrøm CT, Thoefner
MB. Oligofructose overload induces lameness in cattle. J Dairy Sci. 2009
Feb;92(2):607-16.Click here to read
[3] Boyle FG, Wrenn JM, Marsh BB, Anderson WI, Angelosanto FA, McCartney
AL, Lien EL. Safety evaluation of oligofructose: 13 week rat study and in vitro
mutagenicity. Food Chem Toxicol. 2008 Sep;46(9):3132-9. Epub 2008 Jul 3. [4]
Rault-Nania MH, Demougeot C, Gueux E, Berthelot A, Dzimira S, Rayssiguier Y,
Rock E, Mazur A. Inulin supplementation prevents high fructose diet-induced
hypertension in rats. Clin Nutr. 2008 Apr;27(2):276-82. Epub 2008 Mar 21.Click
here to read
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