Folate, the natural form of synthetic folic acid, is found in broccoli, Brussels sprouts, peas, chickpeas, yeast extract, brown rice and fruit including oranges and bananas.
Folic acid supplementation appears to improve cognitive function, particularly memory, among older adults with poor folate status.
Jane Durga, Ph.D., of Wageningen University at Wageningen University reported three years of daily 800 μg folic acid orally bestowed on men and post- menopausal women aged between 50 and 70 the equivalent of a 4.7- to 6.9 years of younger memory in the Jan. 20 issue of The Lancet.
The study evaluated persons with elevated plasma total homocysteine (13 μmol/L or more) who could be expected to benefit from homocysteine-lowering folic acid. Homocysteine is a blood chemical linked both to heart disease and dementia.
All 818 participants also had normal serum vitamin B12 at baseline. Treatment was effective with serum folate concentrations increasing by 576% and plasma homocysteine falling by 26% for the folic acid group compared with placebo.
About Folic Acid
Folic acid is a B vitamin. Our bodies use it to make new cells. Everyone needs folic acid. But for women who can get pregnant, it is really important! If a woman has enough folic acid in her body before she is pregnant, it can help prevent major birth defects of her babyÂ’s brain and spine. These birth defects are neural tube defects or NTDs. Women need to take folic acid every day, starting before they are pregnant to help prevent NTDs. CDC and the U.S. Public Health Service urge every woman who could become pregnant to get 400 micrograms (400 mcg) of synthetic folic acid every day.
Folate helps produce and maintain new cells. This is especially important during periods of rapid cell division and growth such as infancy and pregnancy. Folate is needed to make DNA and RNA, the building blocks of cells. It also helps prevent changes to DNA that may lead to cancer. Both adults and children need folate to make normal red blood cells and prevent anemia. Folate is also essential for the metabolism of homocysteine, and helps maintain normal levels of this amino acid.
Cognitive Function Boosted by Folic Acid Supplements MedPage Today January 19, 2007 Folic acid boosts minds of over-50s, study finds guardian.co.uk January 19, 2007