Systolic blood pressure
High systolic blood pressure treatments and causes.
March 2007
High systolic blood pressure treatments and causes.
March 2007
At middle age or older, some people may notice a gradual rise
in their systolic blood pressure.
In the past, we considered diastolic blood pressure as the
most important component of blood pressure and the primary
target of antihypertensive therapy. [6] However, studies have
shown that systolic blood pressure is an important indicator for
cardiovascular diseases.
Elevated systolic blood pressure results from age-associated
vascular stiffening and reduced compliance that can be
revealed and quantified by analysis of arterial pressure
waveforms. Evaluation of pulse wave velocity together with
other related measures has shown that arterial stiffness
increases with advancing age and other cardiovascular events
such as the metabolic syndrome, diabetes, obesity,
hypercholesterolemia, and elevated C-reactive protein. [1, 2,
5] Some researchers even consider systolic blood pressure as
the most relevant component of blood pressure for
determining risk for cardiovascular and other events in
hypertensive patients, particularly those >50 years of age.
While, several studies show that systolic blood pressure is also
associated with renal disease progression. [4]
In fact, systolic blood pressure is more difficult to control than
diastolic blood pressure, and most middle age and older
hypertensive patients fail to achieve recommended targets. [1]
Younger persons tend toward isolated diastolic hypertension
or combined systolic-diastolic hypertension, primarily driven by
increased peripheral resistance and more effectively treated
by antihypertensive medications; whereas older persons
develop isolated systolic hypertension associated with
increased arterial stiffness that appears to be less amenable
to current therapies. Thus, diastolic pressure in hypertensive
patients often plateaus as patients reach middle-age and
subsequently declines, whereas systolic pressure consistently
rises through the ensuing decades. [1]
Basile J. from Medical University of South Carolina suggested
lifestyle modification, including weight loss and salt restriction
to reduce blood pressure, and may decrease the need for
pharmacologic therapy. He also suggested the initial use of a
diuretic-based or calcium channel blocker-based regimen to
improve the outcome for systolic blood pressure of 160 mm Hg
or more and the diastolic blood pressure of les than 90 mm
Hg. He also recommended two or more drugs to achieve the
present blood pressure goal of less than140 mm Hg for
seniors.
Indapamide SR (a low-dose thiazide-type diuretic) has been
shown effective in lowering the systolic blood pressure. Other
medications include thiazide diuretics, calcium channel
blockers and angiotensin-converting enzyme inhibitor. [3]
Treatment of isolated systolic hypertension is associated with
a reduction in overall cardiovascular mortality of 22%, in
coronary heart disease mortality of 26%, and in stroke
mortality of 33% for seniors. [8]
Tekturna has approved for high blood pressure.
Seven Reasons to drink green tea
ALL RIGHTS RESERVED ZHION 2007 THIS ARTICLE IS FOR YOUR REFERENCE
ONLY. DISCUSS WITH YOUR DOCTOR FOR DETAILS AND TREATMENTS.
[1] Franklin SS. Systolic blood pressure: it's time to take control. Am J Hypertens.
2004 Dec;17(12 Pt 2):49S-54S. [2] Schiffrin EL. Vascular stiffening and arterial
compliance. Implications for systolic blood pressure. Am J Hypertens. 2004
Dec;17(12 Pt 2):39S-48S. [3] London GM. Efficacy of indapamide 1.5 mg,
sustained release, in the lowering of systolic blood pressure. J Hum Hypertens. 2004
Dec;18 Suppl 2:S9-S14. [4] Mentari E, Rahman M. Blood pressure and progression
of chronic kidney disease: importance of systolic, diastolic, or diurnal variation. Curr
Hypertens Rep. 2004 Oct;6(5):400-4. [5] van Trijp MJ, Grobbee DE, Hoes AW, Bots
ML. Prediction of cardiovascular disease on the basis of blood pressure
measurements more reliable with systolic than with diastolic measurement. Ned
Tijdschr Geneeskd. 2003 Jul 26;147(30):1456-9. [6] Strandberg TE, Pitkala K. What
is the most important component of blood pressure: systolic, diastolic or pulse
pressure? Curr Opin Nephrol Hypertens. 2003 May;12(3):293-7. [7] Basile J.
Hypertension in the elderly: a review of the importance of systolic blood pressure
elevation. J Clin Hypertens (Greenwich). 2002 Mar-Apr;4(2):108-12, 119. [8] Campo
C, Segura J, Ruilope LM. Factors influencing the systolic blood pressure response to
drug therapy. J Clin Hypertens (Greenwich). 2002 Jan-Feb;4(1):35-40.
in their systolic blood pressure.
In the past, we considered diastolic blood pressure as the
most important component of blood pressure and the primary
target of antihypertensive therapy. [6] However, studies have
shown that systolic blood pressure is an important indicator for
cardiovascular diseases.
Elevated systolic blood pressure results from age-associated
vascular stiffening and reduced compliance that can be
revealed and quantified by analysis of arterial pressure
waveforms. Evaluation of pulse wave velocity together with
other related measures has shown that arterial stiffness
increases with advancing age and other cardiovascular events
such as the metabolic syndrome, diabetes, obesity,
hypercholesterolemia, and elevated C-reactive protein. [1, 2,
5] Some researchers even consider systolic blood pressure as
the most relevant component of blood pressure for
determining risk for cardiovascular and other events in
hypertensive patients, particularly those >50 years of age.
While, several studies show that systolic blood pressure is also
associated with renal disease progression. [4]
In fact, systolic blood pressure is more difficult to control than
diastolic blood pressure, and most middle age and older
hypertensive patients fail to achieve recommended targets. [1]
Younger persons tend toward isolated diastolic hypertension
or combined systolic-diastolic hypertension, primarily driven by
increased peripheral resistance and more effectively treated
by antihypertensive medications; whereas older persons
develop isolated systolic hypertension associated with
increased arterial stiffness that appears to be less amenable
to current therapies. Thus, diastolic pressure in hypertensive
patients often plateaus as patients reach middle-age and
subsequently declines, whereas systolic pressure consistently
rises through the ensuing decades. [1]
Basile J. from Medical University of South Carolina suggested
lifestyle modification, including weight loss and salt restriction
to reduce blood pressure, and may decrease the need for
pharmacologic therapy. He also suggested the initial use of a
diuretic-based or calcium channel blocker-based regimen to
improve the outcome for systolic blood pressure of 160 mm Hg
or more and the diastolic blood pressure of les than 90 mm
Hg. He also recommended two or more drugs to achieve the
present blood pressure goal of less than140 mm Hg for
seniors.
Indapamide SR (a low-dose thiazide-type diuretic) has been
shown effective in lowering the systolic blood pressure. Other
medications include thiazide diuretics, calcium channel
blockers and angiotensin-converting enzyme inhibitor. [3]
Treatment of isolated systolic hypertension is associated with
a reduction in overall cardiovascular mortality of 22%, in
coronary heart disease mortality of 26%, and in stroke
mortality of 33% for seniors. [8]
Tekturna has approved for high blood pressure.
Seven Reasons to drink green tea
ALL RIGHTS RESERVED ZHION 2007 THIS ARTICLE IS FOR YOUR REFERENCE
ONLY. DISCUSS WITH YOUR DOCTOR FOR DETAILS AND TREATMENTS.
[1] Franklin SS. Systolic blood pressure: it's time to take control. Am J Hypertens.
2004 Dec;17(12 Pt 2):49S-54S. [2] Schiffrin EL. Vascular stiffening and arterial
compliance. Implications for systolic blood pressure. Am J Hypertens. 2004
Dec;17(12 Pt 2):39S-48S. [3] London GM. Efficacy of indapamide 1.5 mg,
sustained release, in the lowering of systolic blood pressure. J Hum Hypertens. 2004
Dec;18 Suppl 2:S9-S14. [4] Mentari E, Rahman M. Blood pressure and progression
of chronic kidney disease: importance of systolic, diastolic, or diurnal variation. Curr
Hypertens Rep. 2004 Oct;6(5):400-4. [5] van Trijp MJ, Grobbee DE, Hoes AW, Bots
ML. Prediction of cardiovascular disease on the basis of blood pressure
measurements more reliable with systolic than with diastolic measurement. Ned
Tijdschr Geneeskd. 2003 Jul 26;147(30):1456-9. [6] Strandberg TE, Pitkala K. What
is the most important component of blood pressure: systolic, diastolic or pulse
pressure? Curr Opin Nephrol Hypertens. 2003 May;12(3):293-7. [7] Basile J.
Hypertension in the elderly: a review of the importance of systolic blood pressure
elevation. J Clin Hypertens (Greenwich). 2002 Mar-Apr;4(2):108-12, 119. [8] Campo
C, Segura J, Ruilope LM. Factors influencing the systolic blood pressure response to
drug therapy. J Clin Hypertens (Greenwich). 2002 Jan-Feb;4(1):35-40.
| A study of 204 married people and 99 single men and women shows that happy marriage may be a boon for blood pressure.Of course, other factors - including diet, exercise, smoking, and stress - also affect blood pressure. Those factors count for everyone, single or married, happy or not. Happy Marriage, Better Blood Pressure WebMD Mar 20, 2008 |